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Figure 6 | PathoGenetics

Figure 6

From: Regulation of TGF-β signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant

Figure 6

Lung phenotype of double heterozygotes. a. Sections through the lungs of newborn wild-type (+/+ +/+), heterozygote for Smad2 (+/+ Smad2/+), heterozygote for Jeff (Jf/+ +/+) and two double heterozygote (Smad2/+ Jf/+) mice: with and without cleft palate. The sections were haematoxylin-eosin stained. Scale bars 200 μm. b. Graphic comparison of the number of airways for three regions of 5.3 × 106 μm2 taken at random and the width of airways for each genotype. P-values were determined using two-tailed T-test comparing each with the wild type.

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