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Figure 4 | PathoGenetics

Figure 4

From: Abnormal autophagy, ubiquitination, inflammation and apoptosis are dependent upon lysosomal storage and are useful biomarkers of mucopolysaccharidosis VI

Figure 4

Inflammation and apoptosis in visceral organs from MPS VI affected rats. (A) Immuno-histochemical analysis with anti-CD68 antibodies and (B) in situ TUNEL analyses of liver, spleen, and kidney sections from 6-month-old normal (NR) and affected (AF) rats. Magnification: 40×. (C) Apoptotic cell count performed on liver, spleen, and kidney sections from 6-month-old NR and AF rats. *P ≤ 0.0001.

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PathoGenetics

ISSN: 1755-8417