Table 2 Gene expression fold-change differences in islets from BLKS mice compared with those from B6 mice
| Â | Â | Â | Interstrain fold difference (BLKS/B6) | Â | Â | Â | |
|---|---|---|---|---|---|---|---|
Probe | Gene | Description | Low Gluc. | High Gluc. | Chromosome | Mb | Genetic Origin |
A_51_P417251 | 6330403K07RIK | RIKEN cDNA | 4.32 | 17.43 | 11 | 71.1 | DBA |
A_52_P532456 | PLAGL1 | pleiomorphic adenoma gene-like 1 | 2.93 | 7.15 | 10 | 12.8 | DBA |
A_51_P113395 | NNT | nicotinamide nucleotide transhydrogenase | 1.94 | 4.22 | 13 | 116.6 | DBA |
A_52_P395228 | NNT | nicotinamide nucleotide transhydrogenase | 2.01 | 4.07 | 13 | 116.6 | DBA |
A_51_P113399 | NNT | nicotinamide nucleotide transhydrogenase | 1.79 | 3.85 | 13 | 116.6 | DBA |
A_51_P422030 | FLJ22709 | hypothetical protein | 1.99 | 3.82 | 8 | 69.8 | DBA |
A_51_P358765 | SPP1 | secreted phosphoprotein 1 | 2.46 | 3.76 | 5 | 103.6 | B6 |
A_51_P253984 | PCP4 | Purkinje cell protein 4 | 1.93 | 3.52 | 16 | 96.9 | DBA |
A_51_P402943 | S100A9 | S100 calcium-binding protein A9 | 1.21 | 3.28 | 3 | 90.8 | DBA |
A_52_P542860 | BTBD9 | BTB domain-containing 9 | 1.99 | 3.27 | 17 | 28.7 | DBA |
A_51_P440682 | CAP1 | CAP, adenylate cyclase-associated protein 1 | 1.82 | 3.17 | 4 | 122.3 | DBA |
A_52_P3029 | AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 1.42 | 2.92 | 17 | 10.9 | DBA |
A_51_P323620 | THYN1 | thymocyte nuclear protein 1 | 1.74 | 2.91 | 9 | 26.9 | other |
A_51_P346165 | AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 1.42 | 2.89 | 17 | 10.9 | DBA |
A_51_P118417 | SCPEP1 | serine carboxypeptidase 1 | 1.70 | 2.87 | 11 | 89.0 | DBA |
A_51_P454873 | NPY | neuropeptide Y | 1.97 | 2.72 | 6 | 49.8 | B6 |
A_51_P491017 | GNPTG | N-acetylglucosamine-1-phosphate transferase, gamma subunit | 1.82 | 2.71 | 17 | 23.4 | DBA |
A_52_P748882 | ENO2 | enolase 2 | 1.62 | 2.58 | 6 | 124.8 | DBA |
A_51_P167535 | FABP3 | fatty acid-binding protein 3 | 1.88 | 2.53 | 4 | 129.8 | DBA? |
A_51_P130028 | ENO2 | enolase 2 | 1.63 | 2.53 | 6 | 124.8 | DBA |
A_51_P101545 | HGFAC | HGF activator | -1.92 | -2.54 | 5 | 34.1 | DBA |
A_51_P337269 | ALDOB | aldolase B, fructose-bisphosphate | -1.17 | -2.66 | 4 | 49.6 | B6 |
A_51_P215627 | PLAC9 | placenta-specific 9 | -1.89 | -2.67 | 14 | 23.6 | DBA |
A_52_P644774 | ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | -1.92 | -2.73 | 11 | 73.0 | DBA |
A_51_P517075 | SERPINF1 | serpin peptidase inhibitor, clade F member 1 | -1.50 | -2.78 | 11 | 75.5 | DBA |
A_52_P213889 | TMC7 | transmembrane channel-like 7 | -1.87 | -2.83 | 7 | 114.5 | DBA |
A_52_P613498 | 4833420G17RIK | RIKEN cDNA | -2.04 | -3.01 | 13 | 116.7 | DBA |
A_51_P376656 | SYNPR | synaptoporin | -2.13 | -3.08 | 14 | 11.4 | DBA |
A_52_P50496 | HLA-A | major histocompatibility complex, class I, A | -2.23 | -3.16 | 17 | 32.1 | DBA |
A_51_P509961 | SLC5A10 | solute carrier family 5 member 10 | -1.21 | -3.24 | 11 | 61.8 | DBA |
A_51_P246677 | REC8L1 | REC8-like 1 | -2.28 | -3.61 | 14 | 50.5 | DBA |
A_51_P392518 | THUMPD1 | THUMP domain-containing 1 | -2.83 | -4.30 | 7 | 115.6 | DBA |
A_51_P146560 | MSLN | mesothelin | -2.31 | -4.36 | 17 | 23.9 | DBA |
A_52_P137500 | AK046255 | Unknown cDNA | -2.70 | -5.06 | X | 131.8 | DBA |
A_51_P443443 | 5830417I10RIK | RIKEN cDNA | -2.75 | -5.46 | 3 | 89.0 | DBA |
A_52_P231729 | H2-Q1 | major histocompatibility complex Q1b | -8.74 | -29.31 | 17 | 33.4 | DBA |