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Table 1 Gene expression fold-change differences in islets from low to high glucose in BLKS and B6 mice

From: Pancreatic islet expression profiling in diabetes-prone C57BLKS/J mice reveals transcriptional differences contributed by DBA loci, including Plagl1 and Nnt

Probe Gene Description Interstrain fold difference (BLKS/B6) Glucose response (fold change)
    Low Gluc. High Gluc. B6 BLKS
A_51_P402943 S100A9 S100 calcium-binding protein A9 1.21 3.28 1.59 4.31
A_51_P438805 TXNIP thioredoxin-interacting protein -1.72 -2.01 4.16 3.56
A_51_P358765 SPP1 secreted phosphoprotein 1 2.46 3.76 2.12 3.24
A_51_P275016 SLC7A3 solute carrier family 7 member 3 1.49 1.97 2.13 2.82
A_51_P372550 CGREF1 cell growth regulator with EF-hand domain 1 1.04 1.65 1.76 2.79
A_51_P510156 LCN2 lipocalin 2 1.98 2.07 2.31 2.41
A_52_P94482 TTYH1 tweety homolog 1 1.73 1.84 2.23 2.37
A_51_P194149 TTR transthyretin -1.31 1.13 1.59 2.37
A_51_P428384 TTYH1 tweety homolog 1 1.58 2.19 1.70 2.36
A_52_P326399 FKBP11 FK506-binding protein 11 1.50 1.48 2.39 2.36
A_51_P130727 FKBP11 FK506-binding protein 11 1.65 1.64 2.34 2.33
A_51_P227275 CSN3 casein kappa 1.43 1.54 2.15 2.31
A_51_P370458 A030006P16RIK RIKEN cDNA 1.01 1.64 1.41 2.29
A_51_P391955 2310032F03RIK RIKEN cDNA 1.10 1.21 2.07 2.27
A_51_P346938 LRG1 leucine-rich alpha-2-glycoprotein 1 1.18 1.17 2.22 2.20
A_52_P187058 NPTX2 neuronal pentraxin II 1.67 2.38 1.51 2.16
A_51_P435911 HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 1.17 1.69 1.46 2.11
A_51_P162955 SERPINA7 serpin peptidase inhibitor member 7 -1.01 1.21 1.69 2.07
A_52_P547328 TRAM1 translocation-associated membrane protein 1 1.09 1.51 1.49 2.06
A_51_P272876 FAM46A family with sequence similarity 46, member A 1.59 1.72 1.88 2.03
A_52_P144310 GAD1 glutamate decarboxylase 1 1.02 -1.23 -1.63 -2.04
A_51_P199352 2310015B20RIK RIKEN cDNA -1.25 -1.71 -1.62 -2.21
  1. Genes are sorted for the subset with BLKS glucose response (fold change) >2 (p < 0.001, Benjamini-Hochberg FDR 0.8).