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Figure 5 | PathoGenetics

Figure 5

From: Pancreatic islet expression profiling in diabetes-prone C57BLKS/J mice reveals transcriptional differences contributed by DBA loci, including Plagl1 and Nnt

Figure 5

Gene expression differences in BLKS islets demonstrate a major contribution by DBA located probes. Gene expression fold-change differences for all probes in the experiment were assigned to either B6, DBA or Other genomes based on chromosomal location. The percentage of probes greater than the fold change threshold (t) are plotted against t for each set of genomically assigned probes. The contributions at a threshold of 1 reflect the baseline genomic contribution of these probes. As the fold change threshold increases, the B6 differences sharply decline, whereas the DBA probes increase their contribution. Above a fold change of 4.5, all of the expression differences are accounted for by DBA assigned probes.

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PathoGenetics

ISSN: 1755-8417