Glucose homeostasis in B6 and BLKS mice. (A) Body weights of B6 and BLKS male mice (n = 13 for each strain) were monitored from 10 weeks to 26 weeks of age. (B) Fasting (4 h) plasma insulin was analyzed in 10-week (n = 13) and 23-week (n = 8) -old B6 and BLKS male mice. (C) Glucose tolerance was assessed in 10 and 23-week-old B6 and BLKS male mice, following an intraperitoneal injection of glucose (2 g/kg). All data represent means and s.e.m. and tested using a two-tailed Student's T-test assuming unequal variances; * P < 0.05, ** P < 0.01, *** P < 0.001.