Figure 2From: Smad4 haploinsufficiency: a matter of dosageWestern analysis of Smad4 -mutant embryonic stem cell lines. SMAD4 western blot analysis demonstrates haploinsufficiency in embryonic stem (ES) and adult intestinal cells from Smad4+/E6sadmice. Upper panel: ES cell lysates loaded at two different protein amounts; lower panel: normal intestinal tissue lysates from wild-type and Smad4+/E6sadmice.Back to article page